Technology

In TSI’s service, individual-specific information is collected from each patient over a period of time (for example, via the Internet) using an efficient, patented user interface in a highly automated process.  This intelligent user interface allows patients to provide the necessary information in the minimum amount of time.  The collected information is supplemented by environmental data, such as weather conditions, which is available from online sources.  In addition, foods and beverages consumed are mapped to their constituent ingredients using a unique database of food ingredients.  For example, using this database, mayonnaise is mapped to egg, mustard, vegetable oil and vinegar.

Temporal analysis of combinations of factors and migraines.

The data is analyzed using TSI’s patented statistical mechanics algorithm, which uses a non-parametric technique to identify the causal factors from millions of possible candidates based on a handful of data points with no adjustable parameters.  This algorithm is very effective in solving such extremely underdetermined or sparse problems.  In the case of migraine, migraine triggers for each patient are identified from the aggregate properties of the statistically significant temporal comparisons of combinations of factors (such as eating a first food and a second food, which is shown in the figure) and the pattern of migraines.